Molecular genetics of blindness, Role of the AU-rich elements (ARE) in the rapid degradation of mRNAs implicated in the inflammatory response of the eye
DNA sequencing (Sanger) and genotyping platform at CRCHUQ-UL; Biobanque Québécoise de la COVID-19 du FRQS at CRCHUQ-UL
The Blakney Lab is a multidisciplinary group of engineers, immunologists and molecular biologists investigating the interactions between RNA, biomaterials and the immune system to prevent and treat disease.
Using structural biology to study signaling, small GTPases and long non-coding RNAs. Elucidating the place of long non-coding RNAs in signaling and cancer with cryo-EM.
Our research is focused on understanding the molecular mechanisms of how small RNA (sRNA) pathways regulate gene expression to influence fertility and animal development. We use C. elegans, a powerful model organism and champion of sRNA research, and we e
The major aim of the lab is to provide biological insights into how intrinsically disordered proteins function in biology. The group uses NMR and other biophysical tools and develops computational tools to study disordered proteins and their interactions.
Structural and Biophysical Core Facility, Hospital for Sick Children; NMR Centre, University of Toronto; Imaging Facility, Hospital for Sick Children; SPARC Molecular Analysis Mass Spectrometry, Hospital for Sick Children